EXAMINE THIS REPORT ON LSD CRYSTAL

From the LSD-sure crystal framework, the facet chain with the lid residue L209EL2 forms considerable hydrophobic contacts with both of those LSD and encompassing residues in TMs III, IV, and V (Determine 4C). If the lid moved aside to show the binding pocket in simulation, quite a few of these contacts broke. We thus hypothesized that L209EL2 acts